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RNA and cancer / Jane Y. Wu, editor

(Cancer treatment and research. ISSN:0927-3042)

データ種別	図書
著者標目	Wu, Jane Y. editor

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配架場所	巻　次	請求記号	登録番号	状　態	コメント	ISBN	刷　年	予約	利用注記
IPE 図書		QU58.7\|\|W959r\|\|2013	41108229			9783642316586

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大きさ	xiii, 245 pages : illustrations (black and white, and colour) ; 25 cm
内容注記	Coupling between transcription and alternative splicing Detection of alternatively spliced or processed RNAs in cancer using oligonucleotide microarray Cancer-associated perturbations in alternative pre-messenger RNA splicing Alternative splicing of tumor suppressors and oncogens MicroRNAs in cancer The perinucleolar compartment : RNA metabolism and cancer Regulation of ARE-mRNA stability by cellular signaling : implications for human cancer Alternative Pre-mRNA splicing, cell death, and cancer Oligonucleotide therapeutics in cancer Clinical perspective on chemo-resistance and the role of RNA processing
件　名	LCSH:RNA LCSH:Cancer -- Genetic aspects LCSH:Cancer -- Gene therapy MESH:Neoplasms -- genetics MESH:RNA -- genetics
一般注記	Includes bibliographical references Summary: In the last decade, it has become increasingly clear that RNA is not simply a messenger molecule directing protein synthesis. Rather, it has multiple, versatile functional roles in cells, especially in mammalian gene regulation, and thereby influences almost every aspect of cellular life. This book reviews recent progress in selected areas of RNA processing in which information of particular relevance to cancer development and therapy has been obtained. It opens by examining the coupling between transcription and splicing. Three subsequent chapters describe in detail cancer-associated aberrant RNAs, new methodology for their detection, and the functional impact on expression of important genes, including oncogenes and tumor suppressor genes. Further topics include the role of microRNAs in cancer and the possible involvement of the perinucleolar compartment. The implications for cancer of regulation of mRNA stability by cellular signaling are discussed, and the importance of splicing defects in the re Also published electronically
分　類	LCC:RC268.4 NLM:2013 D-785 NLM:QZ 200 DC23:616.994042
書誌ID	BB10111257
巻冊次	cased ; ISBN:9783642316586 ; XISBN:9783642316593 cased ; ISBN:3642316581 eBook
NCID	GK51415267

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