Handbook of Parkinson's disease / edited by Rajesh Pahwa, MD, Laverne and Joyce Rider Professor of Neurology, Director, Parkinson's Disease and Movement Disorder Center, University of Kansas Medical Center, Kansas City, USA ; Kelly E. Lyons, PhD, Research Professor of Neurology, Director of Research and Education, Parkinson's Disease and Movement Disorder Center, University of Kansas Medical Center, Kansas City, Kansas, USA